The present case presents an interesting scenario where a patient had a delayed injection-site reaction that did not appear for 11 days post injection, and, when reexposed to XR-NTX at a different location, had a similar more severe reaction with rapid onset with signs of systemic involvement, suggestive of a possible hypersensitivity reaction.
• Atypical very delayed large injection site reactions to the mRNA COVID vaccines appear fairly frequently. They begin about a week after vaccination, persist for several days, resolve without treatment, and have not recurred with second doses.
These results suggest that delayed-onset, injection-site pruritic rashes after mRNA-1273 SARS-CoV2 vaccine administration, lasting up to a week, occur commonly in females, do not lead to serious sequela, and should not deter receipt of the second vaccine dose.
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We have also observed delayed large local reactions to the mRNA-1273 vaccine, with a median onset on day 8 (range, 4 to 11) after the first dose. These reactions had a variable appearance (Figure 1). Here, we report on a series of 12 patients with these reactions, all of which appeared near the injection site after complete resolution of the initial local and systemic symptoms associated with vaccination.
The delayed localized cutaneous reactions developed in a median (range) of 7 (2-12) days after receiving the Moderna COVID-19 vaccine. These reactions occurred at or near the injection site and were described as pruritic, painful, and edematous pink plaques. None of the participants had received the Pfizer-BioNTech vaccine.
The trial also showed that delayed injection-site reactions (defined in that trial as those with an onset on or after day 8) occurred in 244 of the 30,420 participants (0.8%) after the first dose...
COVID-19 vaccine side effects can include Covid arm, a delayed skin reaction. Large red spot or rash appears near injection site after a week after first dose.
Researchers examined 12 cases where patients experienced delayed reactions to the first shot of the Moderna vaccine. The symptoms could take anywhere from four to 11 days after the injection to appear. The average length of time between getting the first dose and having a skin reaction was eight days. Delayed Cutaneous Reactions to mRNA-1273 Vaccine.
While the coronavirus 2019 (COVID-19) vaccine is currently being rolled out, some vaccine recipients are experiencing adverse effects (AEs), one of which includes a delayed large local reaction. This particular reaction is characterized by pain and swelling in the upper arm located at the injection site appearing 7 to 8 days following injection. While this side effect is being commonly referred to as “COVID arm,” experts are warning against this term since the reaction is not caused by ...
Delayed injection-site reactions (those with onset on or after day 8) were noted in 244 participants (0.8%) after the first dose and in 68 participants (0.2%) after the second dose.